Mojo is Lestat de Lioncourt's dog, who he found as a stray, wearing a collar with his name, in Georgetown. shortly before swapping bodies with Raglan James in The Tale of the Body Thief. Mojo is a very large German Shepherd, with a golden, gray, and black coloring and a black muzzle. He instantly takes a liking to Lestat, and can identify him even once he has swapped bodies. Mojo's name and appearance are based on Anne Rice's own pet dog at the time he was introduced to the series.

And before this story moves any further, let me say something about this dog. He isn't going to do anything in this book. He won't save a drowning baby, or rush into a burning building to rouse the inhabitants from near-fatal sleep. He isn't possessed by an evil spirit; he isn't a vampire dog. He's in this narrative simply because I found him in the snow behind that town house in Georgetown, and I loved him, and from that first moment, he seemed somehow to love me. It was all too true to the blind and merciless laws I believe in-the laws of nature, as men say; or the laws of the Savage Garden, as I call them myself. Mojo loved my strength; I loved his beauty. And nothing else ever really mattered at all. - The Tale of the Body Thief

Mojo accompanies Lestat around D.C., before returning with him to New Orleans, eventually being placed in the care of a woman who is a tenant in the building in the Garden District Lestat owns and lives in. In Memnoch the Devil, he is still being cared for by the woman, with Lestat regularly returning to visit him. Being an adult dog in 1991, Mojo presumably died of old age at some point after Memnoch.